Venomous Lizard Puts The Bite On Diabetes

Here is yet another case of a home remedybring it down to a safer level. If low blood sugar
waiting to be discovered. In 2005 the U.S. Foodoccurs, the patient generally consumes
and Drug Administration (FDA) approved a drugcarbohydrates to raise the glucose level to a safe
for the treatment of Type II Diabetes. The druglevel. Type II Diabetes is a chronic disorder
is called Byetta (exenatide). There's nothingcharacterized by resistance to insulin, a deficiency
amazing about that part. New drugs are createdin insulin, and hyperglycemia (high blood sugar or
often.excess glucose).
The almost unbelievable part is where the drugExenatide helps with glucose (blood sugar)
originated. It wasn't produced in a lab. Instead, themanagement in several ways:
active ingredient of Byetta comes from the1. It signals the pancreas to create additional insulin
venomous saliva of the Gila Monster lizard.when glucose levels are too high;
The Gila Monster, once thought to be one of only2. It regulates the liver so that it doesn't produce
two venomous lizards, lives in the deserts of theunneeded glucose; and
southwestern U.S. and northwestern Mexico. The3. It helps slow the rate at which sugar enters the
Gila Monster is a thick-bodied, heavy andbloodstream.
slow-moving lizard. It grows to a maximum lengthStudies showed that another significant effect of
of 2 feet (0.6 m) and preys on small rodents,exenatide use was weight loss. Overweight
fledgling birds, and eggs. It tends to eat animals ondiabetes patients can have more difficulty
the ground that cannot move fast (or at all). Thecontrolling blood sugar levels. The effectiveness of
quick, strong bite of the Gila Monster deliversexenatide for diabetic blood glucose control stems
venomous saliva that is normally not fatal tofrom its ability to activate several glucose control
humans.pathways simultaneously.
Instead, there is a component of the lizard'sByetta (exenatide) is a wonderful drug, although
venom that is extremely helpful to certainits discovery sounds like some kind of horror
humans. A component in the Gila Monster'sstory. One can only imagine gruesome (but
venom has proven remarkably effective in thefictitious) clinical trials where unsuspecting diabetics
control of Type II Diabetes in humans. The Gilaare asked to stick their arms into dark boxes
Monster is a protected species in the U.S.containing Gila Monsters. This discovery sounds like
Fortunately, the exenatide drug can now beone of those "good news/bad news" jokes. For
synthesized in the lab instead of from live animals.example, the doctor says, "The bad news is that
Diabetes is a chronic medical disorder generallythe lizard probably won't release its bite on your
characterized by high blood sugar (glucose) levels,leg for another week. The good news is that
especially after eating. The diabetic patient mustyour diabetes has improved!"
consistently monitor blood sugar levels to keepTo learn more about using available ingredients to
them within a safe range.cure everyday illnesses, please refer to the
When high blood sugar occurs, insulin is used toresource shown below.